Frequency of Occult High‐Grade Squamous Intraepithelial Neoplasia and Invasive Cancer within Anal Condylomata in Men Who Have Sex with Men | Zendy

Hans P. Schlecht | Zendy; Dana Fugelso | Zendy; Ryan Murphy | Zendy; Katiri Wagner | Zendy; John P. Doweiko | Zendy; JoAnn Proper | Zendy; Bruce J. Dezube | Zendy; Lori Panther | Zendy

Open Access

Frequency of Occult High‐Grade Squamous Intraepithelial Neoplasia and Invasive Cancer within Anal Condylomata in Men Who Have Sex with Men

Author(s) -

Hans P. Schlecht,

Dana Fugelso,

Ryan Murphy,

Katiri Wagner,

John P. Doweiko,

JoAnn Proper,

Bruce J. Dezube,

Lori Panther

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/653426

Subject(s) - anal cancer , medicine , men who have sex with men , occult , intraepithelial neoplasia , koilocyte , squamous cell cancer , anus , gynecology , cancer , cervical intraepithelial neoplasia , human immunodeficiency virus (hiv) , cervical cancer , prostate cancer , pathology , virology , surgery , syphilis , alternative medicine

Human papillomavirus causes anal condylomata, high-grade anal intraepithelial neoplasia, and anal squamous cell cancer. We found high-grade intraepithelial neoplasia or squamous cell cancer in 75 (47%) of 159 HIV-seropositive men who have sex with men (MSM) and in 42 (26%) of 160 HIV-seronegative MSM with anal condylomata meriting surgery (P<.001, determined by use of the chi(2) test). Anal condylomata in MSM often harbor high-grade intraepithelial neoplasia and squamous cell cancer.

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