Predictors of Death afterClostridium difficileInfection: A Report on 128 Strain‐Typed Cases from a Teaching Hospital in the United Kingdom | Zendy

Vhairi Wilson | Zendy; Liz Cheek | Zendy; Giovanni Satta | Zendy; Karen WalkerBone | Zendy; Marc Cubbon | Zendy; Diane M. Citron | Zendy; Dale N. Gerding | Zendy; Martin Llewelyn | Zendy

Open Access

Predictors of Death afterClostridium difficileInfection: A Report on 128 Strain‐Typed Cases from a Teaching Hospital in the United Kingdom

Author(s) -

Vhairi Wilson,

Liz Cheek,

Giovanni Satta,

Karen WalkerBone,

Marc Cubbon,

Diane M. Citron,

Dale N. Gerding,

Martin Llewelyn

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/653012

Subject(s) - medicine , hypoalbuminemia , clostridium difficile , metronidazole , disease , mortality rate , strain (injury) , microbiology and biotechnology , antibiotics , biology

We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not associated with any outcome measure. On multivariate analysis, ischemic heart disease and hypoalbuminemia predicted death. Metronidazole treatment in severe disease was associated with a higher rate of treatment failure and death.

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