Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and Endocarditis | Zendy

Sujata M. Bhavnani | Zendy; Christopher M. Rubino | Zendy; Paul G. Ambrose | Zendy; George L. Drusano | Zendy

Open Access

Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and Endocarditis

Author(s) -

Sujata M. Bhavnani,

Christopher M. Rubino,

Paul G. Ambrose,

George L. Drusano

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/652767

Subject(s) - medicine , daptomycin , bacteremia , proportional hazards model , creatine kinase , logistic regression , surgery , cardiology , antibiotics , staphylococcus aureus , vancomycin , biology , bacteria , microbiology and biotechnology , genetics

The objective of this analysis was to evaluate the relationship between daptomycin exposure and the probability of an elevation in the creatine phosphokinase (CPK) level (hereafter, "CPK elevation") in patients with Staphylococcus aureus bacteremia with or without infective endocarditis.

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