Pretreatment Levels of Soluble Cellular Receptors and Interleukin‐6 Are Associated with HIV Disease Progression in Subjects Treated with Highly Active Antiretroviral Therapy | Zendy

Robert C. Kalayjian | Zendy; Rhoderick Machekano | Zendy; Nesrine Rizk | Zendy; Gregory K. Robbins | Zendy; Rajesh T. Gandhi | Zendy; Benigno Rodríguez | Zendy; Richard B. Pollard | Zendy; Michael M. Lederman | Zendy; Alan Landay | Zendy

Open Access

Pretreatment Levels of Soluble Cellular Receptors and Interleukin‐6 Are Associated with HIV Disease Progression in Subjects Treated with Highly Active Antiretroviral Therapy

Author(s) -

Robert C. Kalayjian,

Rhoderick Machekano,

Nesrine Rizk,

Gregory K. Robbins,

Rajesh T. Gandhi,

Benigno Rodríguez,

Richard B. Pollard,

Michael M. Lederman,

Alan Landay

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/652750

Subject(s) - immunology , pathogenesis , viral load , medicine , tumor necrosis factor alpha , cd8 , cytokine , disease , interleukin , t cell , malignancy , immune system , virus

To identify inflammatory pathways that may contribute to the pathogenesis of human immunodeficiency virus (HIV) disease, we explored associations between AIDS or death and different inflammatory markers, including selected soluble tumor necrosis factor superfamily receptors (sTNFRs) and ligands, interleukin (IL)-6, and CD8 T cell activation, in individuals treated with highly active antiretroviral therapy (HAART).

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