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A Phase III Equivalence Trial of Azithromycin versus Benzathine Penicillin for Treatment of Early Syphilis
Author(s) -
Edward W. Hook,
Frieda Behets,
Kathleen Van Damme,
Noro Lantoniaina Rosa Ravelomanana,
Peter A. Leone,
Arlene C. Seña,
David H. Martin,
Carol Langley,
Linda M. McNeil,
Mark Wolff
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/652239
Subject(s) - azithromycin , medicine , syphilis , penicillin , adverse effect , randomized controlled trial , antibiotics , immunology , human immunodeficiency virus (hiv) , microbiology and biotechnology , biology
Syphilis remains an important source of morbidity worldwide. Long-acting penicillin is the only therapy currently recommended for syphilis in much of the world. Because of hesitation to use penicillin for fear of anaphylaxis, there is a need for an effective, well-tolerated alternative to penicillin for syphilis therapy.

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