A Major Gene Controls Leprosy Susceptibility in a Hyperendemic Isolated Population from North of Brazil | Zendy

F. Lázaro | Zendy; Renata Iani Werneck | Zendy; Ciane Cristina Oliveira Mackert | Zendy; Aurélie Cobat | Zendy; Flávia Costa Prevedello | Zendy; Raphaela P. Pimentel | Zendy; Geraldo Mariano Moraes de Macêdo | Zendy; Marco A. Eleuterio | Zendy; Guilherme Vilar | Zendy; Laurent Abel | Zendy; Marília Brasil Xavier | Zendy; Alexandre Alcaïs | Zendy; Marcelo Távora Mira | Zendy

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A Major Gene Controls Leprosy Susceptibility in a Hyperendemic Isolated Population from North of Brazil

Author(s) -

F. Lázaro,

Renata Iani Werneck,

Ciane Cristina Oliveira Mackert,

Aurélie Cobat,

Flávia Costa Prevedello,

Raphaela P. Pimentel,

Geraldo Mariano Moraes de Macêdo,

Marco A. Eleuterio,

Guilherme Vilar,

Laurent Abel,

Marília Brasil Xavier,

Alexandre Alcaïs,

Marcelo Távora Mira

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/652007

Subject(s) - leprosy , population , biology , gene , immunology , genetics , virology , medicine , environmental health

Leprosy is a chronic infectious disease that affects 250,000 new individuals/year worldwide. Genetic analysis has been successfully applied to the identification of host genetic factors affecting susceptibility to leprosy; however, a consensus regarding its mode of inheritance is yet to be achieved.

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