Incidence of Malignancies in HIV‐Infected Patients and Prognostic Role of Current CD4 Cell Count: Evidence from a Large Italian Cohort Study | Zendy

Mattia Prosperi | Zendy; Alessandro CozziLepri | Zendy; Antonella Castagna | Zendy; Cristina Mussini | Zendy; Rita Murri | Zendy; Andrea Giacometti | Zendy; Carlo Torti | Zendy; Andrea Costantini | Zendy; Pasquale Narciso | Zendy; F Ghinelli | Zendy; Andrea Antinori | Zendy; Antonella d’Arminio Monforte | Zendy

Open Access

Incidence of Malignancies in HIV‐Infected Patients and Prognostic Role of Current CD4 Cell Count: Evidence from a Large Italian Cohort Study

Author(s) -

Mattia Prosperi,

Alessandro CozziLepri,

Antonella Castagna,

Cristina Mussini,

Rita Murri,

Andrea Giacometti,

Carlo Torti,

Andrea Costantini,

Pasquale Narciso,

F Ghinelli,

Andrea Antinori,

Antonella d’Arminio Monforte

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/651688

Subject(s) - medicine , incidence (geometry) , cohort , human immunodeficiency virus (hiv) , cohort study , immunology , oncology , physics , optics

The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and non-ADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 person-years of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM.

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