Efflux‐Pump–Derived Multiple Drug Resistance to Ethambutol Monotherapy inMycobacterium tuberculosisand the Pharmacokinetics and Pharmacodynamics of Ethambutol | Zendy

Shashikant Srivastava | Zendy; Sandirai Musuka | Zendy; Carleton M. Sherman | Zendy; Claudia Meek | Zendy; Richard D. Leff | Zendy; Tawanda Gumbo | Zendy

Open Access

Efflux‐Pump–Derived Multiple Drug Resistance to Ethambutol Monotherapy inMycobacterium tuberculosisand the Pharmacokinetics and Pharmacodynamics of Ethambutol

Author(s) -

Shashikant Srivastava,

Sandirai Musuka,

Carleton M. Sherman,

Claudia Meek,

Richard D. Leff,

Tawanda Gumbo

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/651377

Subject(s) - ethambutol , isoniazid , pharmacology , mycobacterium tuberculosis , efflux , pharmacodynamics , medicine , pharmacokinetics , tuberculosis , drug resistance , antibacterial agent , antibiotics , microbiology and biotechnology , biology , pathology , biochemistry

Ethambutol is used for the treatment of tuberculosis in cases where there is isoniazid resistance. We examined the emergence of drug resistance to ethambutol monotherapy in pharmacokinetic-pharmacodynamic studies of a hollow-fiber system.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research