Revaccination with a 23‐Valent Pneumococcal Polysaccharide Vaccine Induces Elevated and Persistent Functional Antibody Responses in Adults Aged ⩾65 Years | Zendy

Susan B. Manoff | Zendy; Charles Liss | Zendy; Michael J. Caulfield | Zendy; Rocio D. Marchese | Zendy; Jeffrey L. Silber | Zendy; John W. Boslego | Zendy; Sandra RomeroSteiner | Zendy; Gowrisankar Rajam | Zendy; Nina E. Glass | Zendy; Cynthia G. Whitney | Zendy; George M. Carlone | Zendy

Open Access

Revaccination with a 23‐Valent Pneumococcal Polysaccharide Vaccine Induces Elevated and Persistent Functional Antibody Responses in Adults Aged ⩾65 Years

Author(s) -

Susan B. Manoff,

Charles Liss,

Michael J. Caulfield,

Rocio D. Marchese,

Jeffrey L. Silber,

John W. Boslego,

Sandra RomeroSteiner,

Gowrisankar Rajam,

Nina E. Glass,

Cynthia G. Whitney,

George M. Carlone

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/651131

Subject(s) - vaccination , medicine , immunology , antibody , pneumococcal polysaccharide vaccine , pneumococcal vaccine , immunoglobulin g , pneumococcal infections , streptococcus pneumoniae , pneumococcal disease , biology , microbiology and biotechnology , antibiotics

Older adults are at high risk of developing invasive pneumococcal disease, but the optimal timing and number of vaccine doses needed to prevent disease among this group are unknown. We compared revaccination with 23-valent pneumococcal polysaccharide vaccine (PN23) with primary vaccination for eliciting initial and persistent functional antibody responses.

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