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The link between human immunodeficiency virus/highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome (HALS) and the use of thymidine analogues has been well established. However, to our knowledge, no relationship has been proven between intracellular levels of stavudine (d4T) and HALS.

clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)

Relationship between HIV/Highly Active Antiretroviral Therapy (HAART)–Associated Lipodystrophy Syndrome and Stavudine‐Triphosphate Intracellular Levels in Patients with Stavudine‐Based Antiretroviral Regimens