Activation of CD8 T Cells Predicts Progression of HIV Infection in Women Coinfected with Hepatitis C Virus | Zendy

Andrea Kovács | Zendy; Roksana Karim | Zendy; Wendy J. Mack | Zendy; Jiaao Xu | Zendy; Zhi Chen | Zendy; Eva A. Operskalski | Zendy; Toni Frederick | Zendy; Alan Landay | Zendy; John C. Voris | Zendy; L SPENCER | Zendy; Mary Young | Zendy; Phyllis C. Tien | Zendy; Michael Augenbraun | Zendy; Howard D. Strickler | Zendy; Lena AlHarthi | Zendy

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Activation of CD8 T Cells Predicts Progression of HIV Infection in Women Coinfected with Hepatitis C Virus

Author(s) -

Andrea Kovács,

Roksana Karim,

Wendy J. Mack,

Jiaao Xu,

Zhi Chen,

Eva A. Operskalski,

Toni Frederick,

Alan Landay,

John C. Voris,

L SPENCER,

Mary Young,

Phyllis C. Tien,

Michael Augenbraun,

Howard D. Strickler,

Lena AlHarthi

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/650997

Subject(s) - coinfection , cd38 , medicine , hepatitis c virus , hazard ratio , immunology , cd8 , hepatitis c , confidence interval , cd4 cd8 ratio , risk factor , proportional hazards model , gastroenterology , virology , virus , immune system , biology , stem cell , lymphocyte subsets , cd34 , genetics

Because activation of T cells is associated with human immunodeficiency virus (HIV) pathogenesis, CD4 and CD8 activation levels in patients coinfected with HIV and hepatitis C virus (HCV) may explain conflicting reports regarding effects of HCV on HIV disease progression.

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