Activity of Elvitegravir, a Once‐Daily Integrase Inhibitor, against Resistant HIV Type 1: Results of a Phase 2, Randomized, Controlled, Dose‐Ranging Clinical Trial
Author(s) -
Andrew Zolopa,
Daniel S Berger,
Harry Lampiris,
Lijie Zhong,
Steven L. Chuck,
Jeffrey Enejosa,
Brian P. Kearney,
Andrew Cheng
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/650698
Subject(s) - elvitegravir , ritonavir , medicine , integrase inhibitor , darunavir , virology , pharmacology , randomized controlled trial , cobicistat , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy
This phase 2, randomized, active-controlled, 48-week study assessed the noninferiority of the human immunodeficiency virus (HIV) integrase inhibitor elvitegravir to comparator ritonavir-boosted protease inhibitor (CPI/r) in treatment-experienced subjects.
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