Hepatitis C Virus (HCV) Quasispecies Complexity and Selection in HCV/HIV‐Coinfected Subjects Treated with Interferon‐Based Regimens | Zendy

Kenneth E. Sherman | Zendy; Susan D. Rouster | Zendy; Sandra Stanford | Zendy; Jason T. Blackard | Zendy; Norah J. Shire | Zendy; Margaret James Koziel | Zendy; Marion G. Peters | Zendy; Raymond T. Chung | Zendy

Open Access

Hepatitis C Virus (HCV) Quasispecies Complexity and Selection in HCV/HIV‐Coinfected Subjects Treated with Interferon‐Based Regimens

Author(s) -

Kenneth E. Sherman,

Susan D. Rouster,

Sandra Stanford,

Jason T. Blackard,

Norah J. Shire,

Margaret James Koziel,

Marion G. Peters,

Raymond T. Chung

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/650490

Subject(s) - hepatitis c virus , coinfection , hepatitis c , hepacivirus , medicine , virology , viral quasispecies , viral load , immunology , interferon , virus

Coinfection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) has emerged as a major cause of morbidity and mortality due to liver disease. Interferon-based therapy response rates have been disappointingly low. Baseline HCV complexity and the relationship between complexity and viral kinetic parameters has not been well described in HCV/HIV-coinfected subjects.

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