Cytomegalovirus Resistance Testing: Pitfalls and Problems for the Clinician
Author(s) -
W. Lawrence Drew
Publication year - 2010
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/650463
Subject(s) - medicine , cytomegalovirus , intensive care medicine , cytomegalovirus infection , interpretation (philosophy) , human cytomegalovirus , cytomegalovirus infections , diagnostic test , virology , immunology , herpesviridae , viral disease , virus , pediatrics , computer science , programming language
In this review, I describe the available assays for detecting resistance of cytomegalovirus (CMV) to antivirals and emphasize the practical utility of the genotypic approach. The indications for such testing and the contraindications are discussed, as are the interpretation of results and the evidence of cross-resistance between antivirals.
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