Open AccessLimited Evolution of Human Immunodeficiency Virus Type 1 in the Thymus of a Perinatally Infected Child
Author(s) -
Franco Scinicariello,
Athena P. Kourtis,
Steven R. Nesheim,
Carlos R. Abramowsky,
Francis K. Lee
Publication year - 2010
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/650453
Subject(s) - virus , cd8 , biology , thymocyte , virology , immunology , immunodeficiency , immunopathology , viral disease , t lymphocyte , immune system
Involvement of the thymus during human immunodeficiency virus (HIV) infection may impair production of naive lymphocytes leading to more rapid depletion, but the characteristics of primary strains in the thymus are not well studied because of the unavailability of tissue in living individuals.
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