Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine
Author(s) -
Maryanne Vahey,
Zhining Wang,
Kent E. Kester,
James F. Cummings,
D. Gray Heppner,
Martin E. Nau,
Opokua OforiAnyinam,
Joe Cohen,
Thierry Coche,
W. Ripley Ballou,
Christian F. Ockenhouse
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/650310
Subject(s) - major histocompatibility complex , virology , malaria , immunology , gene , immunogenicity , malaria vaccine , biology , immune system , plasmodium falciparum , genetics
Patterns of expressed genes in the peripheral blood mononuclear cells of persons who were receiving RTS,S/AS01 or RTS,S/AS02 malaria vaccine and were undergoing experimental challenge with mosquito-borne falciparum malaria were examined to identify markers associated with protection.
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