Comparative Efficacy versus Effectiveness of Initial Antiretroviral Therapy in Clinical Trials versus Routine Care | Zendy

Justin S. Routman | Zendy; James H. Willig | Zendy; Andrew O. Westfall | Zendy; Sarah Abroms | Zendy; Mohit Varshney | Zendy; Sunil Adusumilli | Zendy; Jeroan J. Allison | Zendy; Karen Savage | Zendy; Michael S. Saag | Zendy; Michael J. Mugavero | Zendy

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Comparative Efficacy versus Effectiveness of Initial Antiretroviral Therapy in Clinical Trials versus Routine Care

Author(s) -

Justin S. Routman,

James H. Willig,

Andrew O. Westfall,

Sarah Abroms,

Mohit Varshney,

Sunil Adusumilli,

Jeroan J. Allison,

Karen Savage,

Michael S. Saag,

Michael J. Mugavero

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/650004

Subject(s) - medicine , confidence interval , odds ratio , clinical trial , viral load , logistic regression , retrospective cohort study , antiretroviral therapy , cohort study , cohort , human immunodeficiency virus (hiv) , family medicine

The applicability of clinical trial findings (efficacy) to the routine care setting (effectiveness) may be limited because of study eligibility criteria and volunteer bias. Although well-chronicled in many conditions, the efficacy versus effectiveness of antiretroviral therapy (ART) remains understudied.

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