Association betweenHLA‐B*4001and Lipodystrophy among HIV‐Infected Patients from Thailand Who Received a Stavudine‐Containing Antiretroviral Regimen | Zendy

Wittaya Wangsomboonsiri | Zendy; Surakameth Mahasirimongkol | Zendy; Soranun Chantarangsu | Zendy; Sasisopin Kiertiburanakul | Zendy; Angkana Charoenyingwattana | Zendy; Surat Komindr | Zendy; Chupong Thongnak | Zendy; Taisei Mushiroda | Zendy; Yusuke Nakamura | Zendy; Wasun Chantratita | Zendy; Somnuek Sungkanuparph | Zendy

Open Access

Association betweenHLA‐B*4001and Lipodystrophy among HIV‐Infected Patients from Thailand Who Received a Stavudine‐Containing Antiretroviral Regimen

Author(s) -

Wittaya Wangsomboonsiri,

Surakameth Mahasirimongkol,

Soranun Chantarangsu,

Sasisopin Kiertiburanakul,

Angkana Charoenyingwattana,

Surat Komindr,

Chupong Thongnak,

Taisei Mushiroda,

Yusuke Nakamura,

Wasun Chantratita,

Somnuek Sungkanuparph

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/650003

Subject(s) - stavudine , lipodystrophy , medicine , regimen , odds ratio , lipoatrophy , immunology , zidovudine , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy , viral disease

Stavudine-containing antiretroviral regimens are widely used in developing countries. Stavudine-associated lipodystrophy commonly occurs, without a clear predictable pattern owing to the unknown interaction between stavudine and the host, among patients who received this regimen. The aim of this study was to determine the clinical risk factors and human leukocyte antigen (HLA) alleles associated with stavudine-associated lipodystrophy.

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