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A mean of 9-10 years of human immunodeficiency virus type 1 (HIV-1) infection elapse before clinical AIDS develops in untreated persons, but this rate of disease progression varies substantially among individuals. To investigate host genetic determinants of the rate of progression to clinical AIDS, we performed a multistage genomewide association study.

Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV‐1 Disease Progression to Clinical AIDS