Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV‐1 Disease Progression to Clinical AIDS | Zendy

Joshua T. Herbeck | Zendy; Geoffrey S. Gottlieb | Zendy; Cheryl A. Winkler | Zendy; George W. Nelson | Zendy; Ping An | Zendy; Brandon S. Maust | Zendy; Kim Wong | Zendy; Jennifer L. Troyer | Zendy; James J. Goedert | Zendy; Bailey Kessing | Zendy; Roger Detels | Zendy; Steven M. Wolinsky | Zendy; Jeremy Martinson | Zendy; Susan Buchbinder | Zendy; Gregory D. Kirk | Zendy; Lisa P. Jacobson | Zendy; Joseph B. Margolick | Zendy; Richard A. Kaslow | Zendy; Stephen J. O’Brien | Zendy; James I. Mullins | Zendy

Open Access

Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV‐1 Disease Progression to Clinical AIDS

Author(s) -

Joshua T. Herbeck,

Geoffrey S. Gottlieb,

Cheryl A. Winkler,

George W. Nelson,

Ping An,

Brandon S. Maust,

Kim Wong,

Jennifer L. Troyer,

James J. Goedert,

Bailey Kessing,

Roger Detels,

Steven M. Wolinsky,

Jeremy Martinson,

Susan Buchbinder,

Gregory D. Kirk,

Lisa P. Jacobson,

Joseph B. Margolick,

Richard A. Kaslow,

Stephen J. O’Brien,

James I. Mullins

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/649842

Subject(s) - population , immunology , malignancy , biology , hazard ratio , haplotype , multicenter aids cohort study , locus (genetics) , medicine , oncology , genotype , genetics , virus , viral disease , sida , confidence interval , gene , environmental health

A mean of 9-10 years of human immunodeficiency virus type 1 (HIV-1) infection elapse before clinical AIDS develops in untreated persons, but this rate of disease progression varies substantially among individuals. To investigate host genetic determinants of the rate of progression to clinical AIDS, we performed a multistage genomewide association study.

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