Health Care–AssociatedClostridium difficileInfection in Canada: Patient Age and Infecting Strain Type Are Highly Predictive of Severe Outcome and Mortality
Author(s) -
Mark A. Miller,
Denise Gravel,
Michael R. Mulvey,
Geoffrey Taylor,
David A. Boyd,
Andrew E. Simor,
Michael Gardam,
Allison McGeer,
James Hutchinson,
Dorothy Moore,
Sharon Kelly
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/649213
Subject(s) - medicine , clostridium difficile , intensive care unit , incidence (geometry) , population , colectomy , infection control , strain (injury) , pediatrics , disease , intensive care medicine , microbiology and biotechnology , antibiotics , physics , environmental health , optics , ulcerative colitis , biology
C. difficile infection (CDI) has become an important and frequent nosocomial infection, often resulting in severe morbidity or death. Severe CDI is more frequently seen among individuals infected with the emerging NAP1/027/BI (NAP1) strain and in the elderly population, but the relative importance of these 2 factors remains unclear. We used a large Canadian database of patients with CDI to explore the interaction between these 2 variables.
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