Infrequent Replication of Parvovirus B19 and Erythrovirus Genotypes 2 and 3 among HIV‐Infected Patients with Chronic Anemia
Author(s) -
Tristan Ferry,
Bernard Hirschel,
Thanh Dang,
Pascal Meylan,
Cécile Delhumeau,
Andri Rauch,
Rainer Weber,
Luigia Elzi,
Enos Bernasconi,
Patrick Schmid,
Alexandra Calmy
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/649004
Subject(s) - medicine , parvovirus , anemia , genotype , polymerase chain reaction , parvoviridae , virology , immunology , virus , gene , biology , genetics
We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia. We screened the serum samples of 428 patients by specific ultrasensitive real-time polymerase chain reaction assay. Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients.
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