Persistent Infection with West Nile Virus Years after Initial Infection | Zendy

Kristy O. Murray | Zendy; Christopher M. Walker | Zendy; Emily Herrington | Zendy; Jessica A. Lewis | Zendy; Joseph B. McCormick | Zendy; David W. C. Beasley | Zendy; Robert B. Tesh | Zendy; Susan P. FisherHoch | Zendy

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Persistent Infection with West Nile Virus Years after Initial Infection

Author(s) -

Kristy O. Murray,

Christopher M. Walker,

Emily Herrington,

Jessica A. Lewis,

Joseph B. McCormick,

David W. C. Beasley,

Robert B. Tesh,

Susan P. FisherHoch

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/648731

Subject(s) - west nile virus , virology , amplicon , virus , biology , flaviviridae , chronic infection , medicine , immunology , viral disease , immune system , polymerase chain reaction , gene , genetics

West Nile virus (WNV) RNA was demonstrated in 5 (20%) of 25 urine samples collected from convalescent patients 573-2452 days (1.6-6.7 years) after WNV infection. Four of the 5 amplicons sequenced showed >99% homology to the WNV NY99 strain. These findings show that individuals with chronic symptoms after WNV infection may have persistent renal infection over several years.

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