Bacteriophage Therapy ofSalmonella enterica:A Fresh Appraisal of Bacteriophage Therapy
Author(s) -
Rosanna Capparelli,
Nunzia Nocerino,
Marco Iannaccone,
Danilo Ercolini,
Marianna Parlato,
Chiara Medaglia,
Domenico Iannelli
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/648478
Subject(s) - bacteriophage , lytic cycle , microbiology and biotechnology , phage therapy , salmonella enterica , serotype , virology , salmonella , biology , bacteria , antibody , bacterial virus , virus , escherichia coli , immunology , gene , biochemistry , genetics
The most serious criticisms leveled at bacteriophage therapy are as follows: phages induce neutralizing antibodies, phages are active only when administered shortly after bacterial infection, and phage-resistant bacteria emerge rapidly in the course of therapy.
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