Endoglin in African Children withPlasmodium falciparumMalaria: A Novel Player in Severe Malaria Pathogenesis? | Zendy

Anelia Dietmann | Zendy; Raimund Helbok | Zendy; Peter Lackner | Zendy; Marlene Fischer | Zendy; Markus Reindl | Zendy; Bertrand Lell | Zendy; Saadou Issifou | Zendy; Peter G. Kremsner | Zendy; Erich Schmutzhard | Zendy

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Endoglin in African Children withPlasmodium falciparumMalaria: A Novel Player in Severe Malaria Pathogenesis?

Author(s) -

Anelia Dietmann,

Raimund Helbok,

Peter Lackner,

Marlene Fischer,

Markus Reindl,

Bertrand Lell,

Saadou Issifou,

Peter G. Kremsner,

Erich Schmutzhard

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/648476

Subject(s) - malaria , plasmodium falciparum , pathogenesis , virology , immunology , medicine , biology

Molecular mechanisms involved in the pathogenesis of severe Plasmodium falciparum malaria-specifically, cerebral malaria-are still unclear. Transforming growth factor beta (TGF-beta) family members are important regulators of inflammation that influence malaria pathogenesis. The soluble form of the auxiliary receptor endoglin (sEng) may play a role in malaria pathogenesis.

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