Long‐Term Evolution and Determinants of Renal Function in HIV‐Infected Patients Who Began Receiving Combination Antiretroviral Therapy in 1997–1999, ANRS CO8 APROCO‐COPILOTE | Zendy

Catherine Leport | Zendy; Vincent Bouteloup | Zendy; Jérôme Rossert | Zendy; Michel Garré | Zendy; L. Iordache | Zendy; P. Dellamonica | Zendy; S. Herson | Zendy; François Raffi | Zendy; Geneviève Chêne | Zendy

Open Access

Long‐Term Evolution and Determinants of Renal Function in HIV‐Infected Patients Who Began Receiving Combination Antiretroviral Therapy in 1997–1999, ANRS CO8 APROCO‐COPILOTE

Author(s) -

Catherine Leport,

Vincent Bouteloup,

Jérôme Rossert,

Michel Garré,

L. Iordache,

P. Dellamonica,

S. Herson,

François Raffi,

Geneviève Chêne

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/648445

Subject(s) - indinavir , medicine , renal function , human immunodeficiency virus (hiv) , antiretroviral therapy , sida , body mass index , viral disease , immunology , viral load

Among 1121 patients (90% Caucasian) infected by the human immunodeficiency virus (HIV), the glomerular filtration rate increased (+0.72 mL/min/1.73 m(2)/month) from treatment initiation to month 16 (the rate increase was lower among men and those with low body mass index, AIDS, or receipt of indinavir), then remained stable up to 7 years. Kidney function should be monitored in patients previously exposed to indinavir.

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