Constitutive Expression of the Antimicrobial Peptide RNase 7 Is Associated withStaphylococcus aureusInfection of the Skin | Zendy

Philipp Zanger | Zendy; Johannes Holzer | Zendy; Regina Schleucher | Zendy; Heiko Steffen | Zendy; Birgit Schittek | Zendy; Sabine Gabrysch | Zendy

Open Access

Constitutive Expression of the Antimicrobial Peptide RNase 7 Is Associated withStaphylococcus aureusInfection of the Skin

Author(s) -

Philipp Zanger,

Johannes Holzer,

Regina Schleucher,

Heiko Steffen,

Birgit Schittek,

Sabine Gabrysch

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/648408

Subject(s) - staphylococcus aureus , antimicrobial peptides , skin infection , rnase p , immunology , beta defensin , staphylococcal skin infections , antimicrobial , microbiology and biotechnology , human skin , biology , staphylococcus , medicine , bacteria , rna , gene , genetics , biochemistry

Staphylococcus aureus infections of the skin are a public health problem of growing importance. Antimicrobial peptides in human skin are believed to play an important role in innate defense against intruding pathogens. This study aimed to clarify whether their baseline expression influences the propensity of healthy individuals to develop S. aureus-positive skin infections.

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