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Changes inTrypanosoma cruzi–Specific Immune Responses after Treatment: Surrogate Markers of Treatment Efficacy
Author(s) -
Susana A. Laucella,
Damián PérezMazliah,
Graciela Bertocchi,
M Alvarez,
Gretchen Cooley,
Rodolfo Viotti,
María C. Albareda,
Bruno Lococo,
Miriam Postan,
Alejandro Armenti,
Rick L. Tarleton
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/648072
Subject(s) - trypanosoma cruzi , medicine , surrogate endpoint , immunology , chagas disease , immune system , intensive care medicine , latin americans , immune status , virology , parasite hosting , world wide web , computer science , linguistics , philosophy
As many as 20 million people are living with Trypanosoma cruzi infection in Latin American, yet few receive any treatment. The major limitation in developing and evaluating potential new drugs for their efficacy is the lack of reliable tests to assess parasite burden and elimination.

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