Open AccessReduction inStaphylococcus aureusGrowth and Exotoxin Production and in Vaginal Interleukin 8 Levels Due to Glycerol Monolaurate in Tampons
Author(s) -
Kristi L. Strandberg,
Marnie L. Peterson,
Matthew M. Schaefers,
Laura C. Case,
Melinda C. Pack,
David J. Chase,
Patrick M. Schlievert
Publication year - 2009
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/644614
Subject(s) - staphylococcus aureus , toxic shock syndrome , exotoxin , medicine , microbiology and biotechnology , immunology , toxin , biology , bacteria , genetics
Staphylococcal menstrual toxic shock syndrome depends on vaginal production of exotoxins. Glycerol monolaurate (GML) inhibits Staphylococcus aureus exotoxin production in vitro. The purpose of this study was to determine whether GML, as a tampon fiber finish, inhibits production of exotoxins and the cytokine interleukin 8 (IL-8) during normal tampon use.