Common Features of γδ T Cells and CD8+αβ T Cells Responding to Human Cytomegalovirus Infection in Kidney Transplant Recipients
Author(s) -
Lionel Couzi,
Vincent Pitard,
Sonia Netzer,
Isabelle Garrigue,
MarieEdith Lafon,
JeanFrançois Moreau,
JeanLuc Taupin,
Pierre Merville,
Julie DéchanetMerville
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/644509
Subject(s) - cd8 , immunology , cytotoxic t cell , cytomegalovirus , human cytomegalovirus , cd28 , t cell , immune system , transplant rejection , effector , kidney , biology , virus , medicine , in vitro , herpesviridae , viral disease , endocrinology , biochemistry
Kidney transplant recipients infected with cytomegalovirus (CMV) undergo a persistent gammadelta T cell expansion in their peripheral blood. The anti-CMV function of these cells was previously demonstrated by their ability to kill CMV-infected cells in vitro.
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