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Ruling Out Novel H1N1 Influenza Virus Infection with Direct Fluorescent Antigen Testing
Author(s) -
Nira R. Pollock,
Scott Duong,
Annie Cheng,
Linda L. Han,
Sandra Smole,
James E. Kirby
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/644502
Subject(s) - virology , virus , medicine , antigen , polymerase chain reaction , influenza a virus , predictive value , real time polymerase chain reaction , h1n1 influenza , immunology , biology , covid-19 , gene , disease , pathology , genetics , infectious disease (medical specialty)
We evaluated the ability of direct fluorescent antigen (DFA) influenza tests to identify novel H1N1 influenza virus. DFA results were compared with polymerase chain reaction results. The negative predictive value of DFA testing was at least 96%. Therefore, when performed on specimens of adequate quality, DFA tests can effectively rule out infection due to novel H1N1 virus.

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