Defining Immune Reconstitution Inflammatory Syndrome: Evaluation of Expert Opinion versus 2 Case Definitions in a South African Cohort | Zendy

Lewis Haddow | Zendy; Philippa Easterbrook | Zendy; Anisa Mosam | Zendy; hlanhla G. Khanyile | Zendy; Raveen Parboosing | Zendy; Pravi Moodley | Zendy; MahomedYunus S. Moosa | Zendy

Open Access

Defining Immune Reconstitution Inflammatory Syndrome: Evaluation of Expert Opinion versus 2 Case Definitions in a South African Cohort

Author(s) -

Lewis Haddow,

Philippa Easterbrook,

Anisa Mosam,

hlanhla G. Khanyile,

Raveen Parboosing,

Pravi Moodley,

MahomedYunus S. Moosa

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/630208

Subject(s) - immune reconstitution inflammatory syndrome , medicine , expert opinion , cohort , antiretroviral therapy , disease , tuberculosis , pediatrics , human immunodeficiency virus (hiv) , family medicine , pathology , intensive care medicine , viral load

There is no validated case definition for human immunodeficiency virus-associated immune reconstitution inflammatory syndrome (IRIS). We measured the level of agreement of 2 published case definitions (hereafter referred to as CD1 and CD2) with expert opinion in a prospective cohort of patients who were starting antiretroviral therapy in South Africa.

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