Heterogeneous Vancomycin‐Intermediate Susceptibility Phenotype in Bloodstream Methicillin‐ResistantStaphylococcus aureusIsolates from an International Cohort of Patients with Infective Endocarditis: Prevalence, Genotype, and Clinical Significance
Author(s) -
InGyu Bae,
Jerome J. Federspiel,
José M. Miró,
Christopher W. Woods,
Lawrence Park,
Michael J. Rybak,
Thomas H. Rude,
Suzanne Bradley,
Suzana Bukovski,
Cristina García de la Mària,
Souha S. Kanj,
Tony M. Korman,
Francesc Marco,
David Murdoch,
Patrick Plésiat,
Marta RodríguezCréixems,
Porl Reinbott,
Lisa L. Steed,
Pierre Tattevin,
MarieFrançoise Tripodi,
Karly L. Newton,
G. Ralph Corey,
Vance G. Fowler
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/606027
Subject(s) - infective endocarditis , staphylococcus aureus , microbiology and biotechnology , vancomycin , endocarditis , genotype , bacteremia , methicillin resistant staphylococcus aureus , staphylococcal infections , medicine , micrococcaceae , teicoplanin , biology , antibiotics , antibacterial agent , bacteria , gene , genetics
The significance of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) is unknown. Using a multinational collection of isolates from methicillin-resistant S. aureus (MRSA) infective endocarditis (IE), we characterized patients with IE with and without hVISA, and we genotyped the infecting strains.
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