Heritable Factors Play a Major Role in Determining Host Responses toWuchereria bancroftiInfection in an Isolated South Pacific Island Population | Zendy

Karen T. Cuenco | Zendy; Eric A. Ottesen | Zendy; Steven A. Williams | Zendy; Thomas B. Nutman | Zendy; Cathy Steel | Zendy

Open Access

Heritable Factors Play a Major Role in Determining Host Responses toWuchereria bancroftiInfection in an Isolated South Pacific Island Population

Author(s) -

Karen T. Cuenco,

Eric A. Ottesen,

Steven A. Williams,

Thomas B. Nutman,

Cathy Steel

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/605844

Subject(s) - biology , wuchereria bancrofti , lymphatic filariasis , heritability , immunology , population , host (biology) , filariasis , helminthiasis , helminths , genetics , demography , sociology

It is increasingly recognized that host genetic factors may play an important role in determining the outcome of filarial infections. To test this hypothesis in bancroftian lymphatic filariasis, pedigree data were collected twice during an 18-year period from an isolated Polynesian population living on a Pacific island where lymphatic filariasis is endemic.

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