Role of Uncontrolled HIV RNA Level and Immunodeficiency in the Occurrence of Malignancy in HIV‐Infected Patients during the Combination Antiretroviral Therapy Era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine Cohort | Zendy

Mathias Bruyand | Zendy; Rodolphe Thiébaut | Zendy; S. LawsonAyayi | Zendy; Pierre Joly | Zendy; Annie J. Sasco | Zendy; P. Mercié | Zendy; J.L. Pellegrin | Zendy; D. Neau | Zendy; François Dabis | Zendy; Philippe Morlat | Zendy; Geneviève Chêne | Zendy; Fabrice Bonnet | Zendy

Open Access

Role of Uncontrolled HIV RNA Level and Immunodeficiency in the Occurrence of Malignancy in HIV‐Infected Patients during the Combination Antiretroviral Therapy Era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine Cohort

Author(s) -

Mathias Bruyand,

Rodolphe Thiébaut,

S. LawsonAyayi,

Pierre Joly,

Annie J. Sasco,

P. Mercié,

J.L. Pellegrin,

D. Neau,

François Dabis,

Philippe Morlat,

Geneviève Chêne,

Fabrice Bonnet

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/605594

Subject(s) - medicine , sida , incidence (geometry) , hazard ratio , proportional hazards model , cohort , human immunodeficiency virus (hiv) , immunopathology , immunodeficiency , lentivirus , antiretroviral therapy , viral load , malignancy , immunology , viral disease , immune system , confidence interval , physics , optics

Human immunodeficiency virus (HIV)-infected patients are at higher risk of malignancies. In addition to traditional determinants, a specific deleterious effect of HIV and immunodeficiency is speculated. We aimed at studying the association between immunological and virological characteristics of HIV-infected patients in care and the risk of acquired immunodeficiency syndrome (AIDS)-defining and non-AIDS-defining malignancies.

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