Heparin‐Binding Protein: An Early Marker of Circulatory Failure in Sepsis | Zendy

Adam Linder | Zendy; Bértil Christensson | Zendy; Heiko Herwald | Zendy; Lars Björck | Zendy; Per Åkesson | Zendy

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Heparin‐Binding Protein: An Early Marker of Circulatory Failure in Sepsis

Author(s) -

Adam Linder,

Bértil Christensson,

Heiko Herwald,

Lars Björck,

Per Åkesson

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/605563

Subject(s) - procalcitonin , sepsis , medicine , systemic inflammatory response syndrome , septic shock , circulatory system , c reactive protein , shock (circulatory) , white blood cell , gastroenterology , prospective cohort study , circulatory failure , inflammation

The early detection of circulatory failure in patients with sepsis is important for successful treatment. Heparin-binding protein (HBP), released from activated neutrophils, is a potent inducer of vascular leakage. In this study, we investigated whether plasma levels of HBP could be used as an early diagnostic marker for severe sepsis with hypotension.

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