Pegylated Interferon and Ribavirin Promote Early Evolution of Nonstructural 5A Protein in Individuals with Hepatitis C Who Demonstrate a Response to Treatment | Zendy

Mamta K. Jain | Zendy; HeJun Yuan | Zendy; Beverley AdamsHuet | Zendy; Amanda Reeck | Zendy; Janel L Shelton | Zendy; Nahid Attar | Zendy; Song Zhang | Zendy; Avidan U. Neumann | Zendy; D. Spencer Carney | Zendy; Michael Gale | Zendy; William M. Lee | Zendy

Open Access

Pegylated Interferon and Ribavirin Promote Early Evolution of Nonstructural 5A Protein in Individuals with Hepatitis C Who Demonstrate a Response to Treatment

Author(s) -

Mamta K. Jain,

HeJun Yuan,

Beverley AdamsHuet,

Amanda Reeck,

Janel L Shelton,

Nahid Attar,

Song Zhang,

Avidan U. Neumann,

D. Spencer Carney,

Michael Gale,

William M. Lee

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/605475

Subject(s) - viral quasispecies , ns5a , hepatitis c virus , ribavirin , virology , hepatitis c , viral evolution , hepacivirus , biology , interferon , pegylated interferon , virus , immunology , medicine , rna , genetics , gene

Hepatitis C virus (HCV) quasispecies diversity is more likely to affect early viral decline during treatment of hepatitis C than is having human immunodeficiency virus (HIV) infection. We evaluated the influence of HCV therapy on changes in the nonstructural 5A (NS5A) protein.

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