Open AccessTrends in the Epidemiology of Human G1P[8] Rotaviruses: A Hungarian Study
Author(s) -
Krisztiàn Bányai,
Jon R. Gentsch,
Vito Martella,
Ágnes Bogdán,
Viktória Havasi,
Péter Kisfali,
Alíz Szabó,
Ilona Mihály,
Péter Molnár,
Béla Melegh,
György Szűcs
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/605052
Subject(s) - rotavirus , genotype , virology , biology , molecular epidemiology , epidemiology , phylogenetic tree , population , strain (injury) , outbreak , genetics , geography , gene , virus , medicine , environmental health , anatomy
Epidemiological trends of the globally most common rotavirus genotype, G1P[8], were investigated in Hungary during a 16-year period by sequencing and phylogenetic analysis of the surface antigens. Antigen shift among epidemiologically major G1P[8] strains was observed in 6 seasons, as indicated by changes in the sublineages of the G1 VP7 and the P[8] VP4 genes. The temporal clustering of some rotavirus VP4 and VP7 gene sublineages and the periodic emergence and/or resurgence of previously unrecognized rotavirus sublineages in the study population suggest a dynamic nature for these common strains. Recently established international strain surveillance networks may help to identify and track the spread of epidemiologically important rotavirus strains across countries and continents.
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