Rate of Accumulation of Thymidine Analogue Mutations in Patients Continuing to Receive Virologically Failing Regimens Containing Zidovudine or Stavudine: Implications for Antiretroviral Therapy Programs in Resource‐Limited Settings | Zendy

Alessandro CozziLepri | Zendy; Andrew Phillips | Zendy; Javier MartínezPicado | Zendy; Antonella d’Arminio Monforte | Zendy; Christine Katlama | Zendy; AnnBrit Eg Hansen | Zendy; Andrzéj Horban | Zendy; Johann Bruun | Zendy; Bonaventura Clotet | Zendy; Jens Lundgren | Zendy

Open Access

Rate of Accumulation of Thymidine Analogue Mutations in Patients Continuing to Receive Virologically Failing Regimens Containing Zidovudine or Stavudine: Implications for Antiretroviral Therapy Programs in Resource‐Limited Settings

Author(s) -

Alessandro CozziLepri,

Andrew Phillips,

Javier MartínezPicado,

Antonella d’Arminio Monforte,

Christine Katlama,

AnnBrit Eg Hansen,

Andrzéj Horban,

Johann Bruun,

Bonaventura Clotet,

Jens Lundgren

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/604731

Subject(s) - zidovudine , stavudine , reverse transcriptase inhibitor , confidence interval , medicine , reverse transcriptase , viral load , thymidine , virology , human immunodeficiency virus (hiv) , oncology , antiretroviral therapy , immunology , pharmacology , biology , viral disease , rna , genetics , dna , gene

Because changes in antiretroviral therapy in resource-limited settings (RLSs) are delayed until patients experience immunological or clinical failure, it is important to be able to estimate the consequences in terms of accumulation of thymidine analogue (TA) mutations (TAMs).

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