A Retrospective Evaluation of Completion Rates, Total Cost, and Adverse Effects for Treatment of Latent Tuberculosis Infection in a Public Health Clinic in Central Massachusetts | Zendy

Heather Young | Zendy; Mireya Wessolossky | Zendy; Jeanne Ellis | Zendy; Martin Kaminski | Zendy; Jennifer S. Daly | Zendy

Open Access

A Retrospective Evaluation of Completion Rates, Total Cost, and Adverse Effects for Treatment of Latent Tuberculosis Infection in a Public Health Clinic in Central Massachusetts

Author(s) -

Heather Young,

Mireya Wessolossky,

Jeanne Ellis,

Martin Kaminski,

Jennifer S. Daly

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/600394

Subject(s) - medicine , adverse effect , tuberculosis , isoniazid , latent tuberculosis , retrospective cohort study , pediatrics , surgery , mycobacterium tuberculosis , pathology

Completion rates, total cost, and adverse effects were compared for patients in central Massachusetts treated for latent tuberculosis infection with 9 months of isoniazid or 4 months of rifampin. Although the adverse effects were similar between the 2 groups, 4 months of rifampin was associated with significantly better completion rates and less hepatotoxicity yet higher total cost.

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