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A Quantitative Assessment of the Efficacy of Surgical and N95 Masks to Filter Influenza Virus in Patients with Acute Influenza Infection
Author(s) -
Douglas Johnson,
Julian Druce,
Chris Birch,
M. Lindsay Grayson
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/600041
Subject(s) - medicine , respirator , virus , virology , reverse transcription polymerase chain reaction , polymerase chain reaction , orthomyxoviridae , influenza a virus , covid-19 , pathology , infectious disease (medical specialty) , biology , gene , messenger rna , biochemistry , materials science , composite material , disease
We assessed the in vivo efficacy of surgical and N95 (respirator) masks to filter reverse transcription-polymerase chain reaction (RT-PCR)-detectable virus when worn correctly by patients with laboratory-confirmed acute influenza. Of 26 patients with a clinical diagnosis of influenza, 19 had the diagnosis confirmed by RT-PCR, and 9 went on to complete the study. Surgical and N95 masks were equally effective in preventing the spread of PCR-detectable influenza.

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