Open AccessAcuteChlamydia pneumoniaeReinfection Accelerates the Development of Insulin Resistance and Diabetes in Obese C57BL/6 Mice
Author(s) -
Chengming Wang,
Dongya Gao,
Bernhard Kaltenboeck
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/599796
Subject(s) - insulin resistance , chlamydia , diabetes mellitus , medicine , obesity , immunology , insulin , endocrinology
Epidemiological and pathological evidence links highly prevalent pathogens to chronic inflammatory diseases, such as type 2 diabetes. Animal models contribute critically to the mechanistic understanding of infectious enhancement of inflammatory diseases, which share insulin resistance as the central pathophysiological defect.
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