High Frequency of Antiretroviral Drug Resistance among HIV‐Infected Adults Receiving First‐Line Highly Active Antiretroviral Therapy in N’Djamena, Chad
Author(s) -
Donato Koyalta,
Charlotte Charpentier,
Jatibi Beassamda,
Elisabeth Rey,
Ali SiMohamed,
Noël DjemadjiOudjeil,
Laurent Bélec
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/599611
Subject(s) - medicine , drug resistance , virology , regimen , viral load , antiretroviral therapy , resistance mutation , human immunodeficiency virus (hiv) , sida , lentivirus , viral disease , immunology , microbiology and biotechnology , polymerase chain reaction , biology , reverse transcriptase , biochemistry , gene
Antiretroviral drug resistance was evaluated in 88 adults infected with human immunodeficiency virus, most with subtype CRF11_cpx, who had received a first-line antiretroviral regimen for 6 months, in N'Djamena, Chad. A total of 47 patients (53%) had detectable viral load at month 6, and 56 (64%) had at least 1 antiretroviral resistance mutation observed.
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