Expression of Pls (Plasmin Sensitive) inStaphylococcus aureusNegative forplsReduces Adherence and Cellular Invasion and Acts by Steric Hindrance | Zendy

Muzaffar Hussain | Zendy; Daniel W. Schafer | Zendy; Katri Juuti | Zendy; Georg Peters | Zendy; Bettina HaslingerLöffler | Zendy; Pentti Kuusela | Zendy; Bhanu Sinha | Zendy

Open Access

Expression of Pls (Plasmin Sensitive) inStaphylococcus aureusNegative forplsReduces Adherence and Cellular Invasion and Acts by Steric Hindrance

Author(s) -

Muzaffar Hussain,

Daniel W. Schafer,

Katri Juuti,

Georg Peters,

Bettina HaslingerLöffler,

Pentti Kuusela,

Bhanu Sinha

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/599359

Subject(s) - staphylococcus aureus , plasmin , microbiology and biotechnology , adhesion , steric effects , protein expression , chemistry , biology , bacteria , biochemistry , enzyme , stereochemistry , gene , genetics , organic chemistry

The methicillin-resistant Staphylococcus aureus (MRSA) surface protein Pls (plasmin sensitive) reduces adhesion to host proteins and cellular invasiveness by an unknown mechanism that requires Pls expression. Here, we tested the effect of Pls expression using different pls-negative backgrounds.

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