High Prevalence of AsymptomaticPlasmodium falciparumInfections in a Highland Area of Western Kenya: A Cohort Study | Zendy

Frederick N. Baliraine | Zendy; Yaw A. Afrane | Zendy; Dolphine A. Amenya | Zendy; Mariangela Bonizzoni | Zendy; David M. Menge | Zendy; Goufa Zhou | Zendy; Daibin Zhong | Zendy; Anne Vardo-Zalik | Zendy; Andrew K. Githeko | Zendy; Guiyun Yan | Zendy

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High Prevalence of AsymptomaticPlasmodium falciparumInfections in a Highland Area of Western Kenya: A Cohort Study

Author(s) -

Frederick N. Baliraine,

Yaw A. Afrane,

Dolphine A. Amenya,

Mariangela Bonizzoni,

David M. Menge,

Goufa Zhou,

Daibin Zhong,

Anne Vardo-Zalik,

Andrew K. Githeko,

Guiyun Yan

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/599317

Subject(s) - asymptomatic , malaria , epidemiology , plasmodium falciparum , cohort , transmission (telecommunications) , medicine , cohort study , immunology , parasitemia , biology , electrical engineering , engineering

Transmission of malaria in an area of hypoendemicity in the highlands of western Kenya is not expected to lead to rapid acquisition of immunity to malaria. However, the subpopulation of individuals with asymptomatic Plasmodium falciparum infection may play a significant role as an infection reservoir and should be considered in malaria-control programs. Determination of the spatiotemporal dynamics of asymptomatic subpopulations provides an opportunity to estimate the epidemiological importance of this group to malaria transmission.

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