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Nasal‐Associated Lymphoid Tissue and Olfactory Epithelium as Portals of Entry forBurkholderia pseudomalleiin Murine Melioidosis
Author(s) -
Suzzanne Owen,
Michael R. Batzloff,
Fatemeh Chehrehasa,
Adrian Cuda Banda Meedeniya,
Yveth Casart,
CarieAnne Logue,
Robert G. Hirst,
Ian R. Peak,
Alan MackaySim,
Ifor R. Beacham
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/599210
Subject(s) - burkholderia pseudomallei , melioidosis , pathology , olfactory epithelium , biology , epithelium , respiratory tract , lymphatic system , respiratory epithelium , nasal cavity , olfactory mucosa , olfactory system , immunology , medicine , respiratory system , anatomy , bacteria , genetics , neuroscience
Burkholderia pseudomallei, the causative agent of melioidosis, is generally considered to be acquired via inhalation of dust or water droplets from the environment. In this study, we show that infection of the nasal mucosa is potentially an important portal of entry in melioidosis.

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