Diagnostic Performance of the Cytomegalovirus (CMV) Antigenemia Assay in Patients with CMV Gastrointestinal Disease | Zendy

EunYoung Jang | Zendy; Seong Yeon Park | Zendy; Eun Jung Lee | Zendy; Eun Hee Song | Zendy; Yong Pill Chong | Zendy; SangOh Lee | Zendy; SangHo Choi | Zendy; Jun Hee Woo | Zendy; Yang Soo Kim | Zendy; SungHan Kim | Zendy

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Diagnostic Performance of the Cytomegalovirus (CMV) Antigenemia Assay in Patients with CMV Gastrointestinal Disease

Author(s) -

EunYoung Jang,

Seong Yeon Park,

Eun Jung Lee,

Eun Hee Song,

Yong Pill Chong,

SangOh Lee,

SangHo Choi,

Jun Hee Woo,

Yang Soo Kim,

SungHan Kim

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/599116

Subject(s) - medicine , cytomegalovirus , gastrointestinal disease , confidence interval , betaherpesvirinae , gastroenterology , cytomegalovirus infection , disease , viral disease , immunology , herpesviridae , human cytomegalovirus , virus

Of 149 patients with suspected cytomegalovirus (CMV) gastrointestinal disease, 51 (36%) confirmed cases, 6 (4%) probable cases, and 64 (45%) instances of non-CMV gastrointestinal disease were analyzed using the CMV antigenemia assay; 22 patients (5%) with indeterminate gastrointestinal disease were excluded. The sensitivity and specificity of the CMV antigenemia assay (defined as detection of > or =1 positive cells per 200,000 leukocytes) for diagnosis of CMV gastrointestinal disease were 54% (95% confidence interval, 41%-68%) and 88% (95% confidence interval, 77%-94%), respectively.

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