Presence of a Multidrug‐Resistance Mutation in an HIV‐2 Variant Infecting a Treatment‐Naive Individual in Caio, Guinea Bissau | Zendy

Sabelle Jallow | Zendy; Tim Vincent | Zendy; Aleksandra Leligdowicz | Zendy; Thushan I. de Silva | Zendy; Carla van Tienen | Zendy; Abraham Alabi | Zendy; Ramu SargeNjie | Zendy; Peter Aaby | Zendy; Tumani Corrah | Zendy; Hilton Whittle | Zendy; Assan Jaye | Zendy; Guido Vanham | Zendy; Sarah Rowland–Jones | Zendy; Wouter Janssens | Zendy

Open Access

Presence of a Multidrug‐Resistance Mutation in an HIV‐2 Variant Infecting a Treatment‐Naive Individual in Caio, Guinea Bissau

Author(s) -

Sabelle Jallow,

Tim Vincent,

Aleksandra Leligdowicz,

Thushan I. de Silva,

Carla van Tienen,

Abraham Alabi,

Ramu SargeNjie,

Peter Aaby,

Tumani Corrah,

Hilton Whittle,

Assan Jaye,

Guido Vanham,

Sarah Rowland–Jones,

Wouter Janssens

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/599107

Subject(s) - medicine , drug resistance , mutation , multiple drug resistance , virology , resistance mutation , population , new guinea , human immunodeficiency virus (hiv) , transmission (telecommunications) , genetics , environmental health , biology , gene , ethnology , polymerase chain reaction , reverse transcriptase , electrical engineering , engineering , history

We report the possible transmission of drug-resistant human immunodeficiency virus type 2. A 66-year-old woman from rural Guinea Bissau who had no obvious antiretroviral exposure was found to harbor a variant with the multidrug-resistance mutation Q151M. Finding this mutation among a drug-naive population presents an important public health issue that needs to be addressed for treatment to be effective.

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