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Sensitivity of Mouse Bioassay in Clinical Wound Botulism
Author(s) -
Charlotte Wheeler,
Gregory B. Inami,
Janet C. MohleBoetani,
Duc J. Vugia
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/599029
Subject(s) - bioassay , medicine , botulism , toxin , flaccid paralysis , gold standard (test) , gastroenterology , paralysis , surgery , microbiology and biotechnology , biology , genetics
California has an ongoing epidemic of wound botulism (WB) among injection drug users (IDUs). We retrospectively studied a cohort of patients with WB and determined the sensitivity of the mouse bioassay-the gold standard laboratory test for confirmation of botulism-in verifying WB.

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