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Dried Umbilical Cords in the Retrospective Diagnosis of Congenital Cytomegalovirus Infection as a Cause of Developmental Delays
Author(s) -
Shin Koyano,
Naoki Inoue,
Tsunehisa Nagamori,
Hainian Yan,
Hideomi Asanuma,
Kazuyori Yagyu,
Masaya Osaki,
Chizuru Seiwa,
Kenji Fujieda
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/598506
Subject(s) - medicine , cytomegalovirus , calcification , betaherpesvirinae , pediatrics , cytomegalovirus infections , human cytomegalovirus , retrospective cohort study , cytomegalovirus infection , herpesviridae , immunology , viral disease , pathology , virus
To clarify the impact of congenital cytomegalovirus (CMV) infection on developmental disabilities, 20 children with disabilities of unknown cause were analyzed. Five children were CMV positive and had no clinical manifestations at birth. Intracranial calcification was observed in 4 cases. Thus, congenital CMV infection is a significant cause of developmental disabilities.

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