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Transcription Analysis of the Extracellular Adherence Protein fromStaphylococcus aureusin Authentic Human Infection and In Vitro
Author(s) -
Insa Joost,
Daniel Blass,
Marc Burian,
Christiane Goerke,
Christiane Wolz,
Lutz von Müller,
Karsten Becker,
Klaus Preissner,
Mathias Herrmann,
Markus Bischoff
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/598484
Subject(s) - staphylococcus aureus , in vivo , in vitro , microbiology and biotechnology , wound healing , biology , transcription (linguistics) , transcription factor , gentamicin protection assay , immunology , bacteria , gene , genetics , western blot , linguistics , philosophy
Wound infections caused by Staphylococcus aureus are associated with significant morbidity and mortality. The staphylococcal extracellular adherence protein (Eap) has been shown to delay wound healing by interfering with host defense and angiogenesis, yet the expression of Eap in the human wound is required to exert these functions.

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